Membrane Cleaning Chemical of RO membranes will help to add to its performance and will extend its useful life. The main anxiety with cleaning is that it be supposed to be done before the situation gets too bad as then the membrane may become fouled and will have to be replaced. Membrane Cleaning Chemical should be undertaken whenever the infuse flux, differential pressure, or conductivity changes to undesirable values. However, it is better to clean the membrane frequently after a predetermined interval. Each type of fouling requires a diverse cleaning approach depending on the water supply, membrane fouling may be inorganic, organic, microbiological, or a combination.